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FDA Approval of Exenatide, an Injectable GLP-1 Agonist The approval of exenatide 1.2 mL and 2.4 mL prefilled pen injection, referencing BYETTA, reflects the Companys deep innovation and regulatory capabilities in complex pharmaceuticals and its ability to successfully develop this first synthetic generic peptide
Its unique ability to target hard-to-reach persister cells makes rifabutin valuable when standard Lyme disease antibiotics prove ineffective
Informed consent should include what is known, what is unknown, whether the formulation is approved, and what alternatives have stronger evidence
Heres a look at common biologic classes and their half-lives: o Humira (adalimumab): 68 weeks o Enbrel (etanercept): 2 weeks o Remicade (infliximab): 46 weeks o Cosentyx (secukinumab): 4 weeks o Stelara (ustekinumab): 12 weeks o Tremfya (guselkumab): 8 weeks o Xeljanz (tofacitinib): 12 weeks o Rinvoq (upadacitinib): 12 weeks A common approach physicians might take to accommodate for the variation in drug half-lives is to stop one full dosing interval before major implant surgery for each biologic, with consideration for a longer hold where theres a high risk for infection or poor wound healing
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