People with MCAS are also more likely to have side effects from B12 supplementation
Patients should also be aware that folate supplementation should not be started before B12 deficiency has been treated, as doing so can precipitate or worsen neurological complications
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Kiyoshi Okada, Hiroyuki Tanaka, Ko Temporin, Michio Okamoto, Yusuke Kuroda, Hisao Moritomo, Tsuyoshi Murase, Hideki Yoshikawa, Methylcobalamin increases Erk1/2 and Akt activities through the methylation cycle and promotes nerve regeneration in a rat sciatic nerve injury model, Experimental Neurology, Volume 222, Issue 2, April 2010, Pages 191-203 Tanaka, H
If switching to a plant-based diet, it usually takes years before a clinically manifest deficiency develops, especially taking the reserve capacity of the body into consideration