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Adiponectin, an anti-inflammatory adipokine, typically rises

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AR42J cells, a rat pancreatic acinar-derived cell line but which shows some islet characteristics has also been studied

ArticlePubMed 93

Importantly, delactylase enzymes, such as HDAC1, HDAC3, and SIRT family members, have been shown to remove lactyl groups in vitro, suggesting that non-histone lactylation is dynamically reversible and may constitute a regulatory network parallel to acetylation [94]