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Dosing Schedules from Published Research Phase 2 Trial Dose Groups The Phase 2 clinical trial published in NEJM employed the following dose groups, all administered via subcutaneous injection once weekly: Scroll sideways to view the full table on mobile
The reconstitution-related concern with these formats is not about mixing it is about whether the molecule reaches systemic circulation at all
Example calculation: (15 30) 100 = 50 units
This knowledge also explains why oral B12 supplementation may be ineffective in intrinsic factor deficiency, requiring alternative routes like sublingual, nasal, or injectable B12 to bypass the intrinsic factor-dependent absorption pathway
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