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The value proposition proves compelling for long-term users where $2,000-5,000 annual savings justify 3-6 week international shipping, group buy coordination complexity, cryptocurrency payment requirements, and accepting 5-10% disappointment risk

Withdrawal rates due to adverse effects serve as a practical measure of real-world tolerability, making this finding especially relevant for clinical application

Generally, L-carnitine is pretty safe, but taking high doses can sometimes lead to diarrhea and intestinal discomfort

This oversight allows for adjustments based on individual responses and minimizes risks

10.1186/s12951-021-00951-z 289 WangZ.LiW.WangY.LiX.HuangL.LiX