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van der Heide V, Jangra S, Cohen P, Rathnasinghe R, Aslam S, Aydillo T, et al

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Simple timing framework Baseline Discuss baseline labs before starting or escalating, especially with diabetes, gallbladder history, pancreatitis history, kidney disease, liver disease, or cardiovascular concerns

Testing and monitoring If you have concerns about mercury exposure, discuss testing options with your healthcare provider

Furthermore, improvements in systemic biomarkers, which occur in some interventional studies and include the lowering of CRP, which is observed with periodontal therapy, may be partly a reflection of the influence on non-specific infections or improved oral hygiene, rather than a direct periodontal-dependent cardiovascular effect