Endocrinology 140:53565363 Hansen L, Hartmann B, Minco H, Holst JJ (2004) Glucagon-like peptide-1 secretion is influenced by perfusate glucose concentration and by a feedback mechanism involving somatostatin in isolated perfused porcine ileum
This shift appears to be influenced by a growing awareness of the benefits associated with GLP-1 receptor agonists, which are recognized for their efficacy in weight management and glycemic control
Many interventions have been tested in clinical trials but, to date, the most promising results have been from the anti-CD3 monoclonal antibody teplizumab, low-dose anti-thymocyte globulin (ATG), and the anti-TNF drug, golimumab
Protocol compliance affects outcomes substantially
However, it is important to maintain a healthy diet and exercise regimen to continue to enjoy the excellent results