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In mice, hepatocyte Dpp4 expression increases with obesity (82), and selective elimination of Dpp4 in the liver is associated with reduced levels of soluble DPP-4 in the plasma (82, 83)
This overall average calorie intake, the paper notes, exceeds expert recommendations for individuals on GLP-1RAs (typically 1,2001,500 kcal/day for females and 1,5001,800 kcal/day for males)
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