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GSK-3 inhibition through GLP-1R allosteric activation mediates the neurogenesis promoting effect of P7C3 after cerebral ischemic/reperfusional injury in mice
While GLP-1 medications treat type 2 diabetes and obesity by mimicking this hormone, its also possible to promote GLP-1 production naturally
Additionally, a healthier gut can lead to increased energy levels and improved mood
While we await final FDA approval, this represents another exciting development in the obesity medicine pipeline
That said, Wegovy is FDA-approved and widely prescribed for weight loss with excellent clinical responses, while retatrutide is still an investigational drug only available through clinical trials and its long-term safety and tolerability are still being studied
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