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In recent years, the landscape of weight management and diabetes treatment has undergone a remarkable transformation, particularly with the introduction of glucagon-like peptide-1 (GLP-1) receptor agonists
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Springer Verlag
It is known that carnitine has a role in membrane stabilization and function
In fact, the GLP- 1 receptor-cAMP-PKA axis stimulates the growth of beta cells by activating the transducer of regulated cAMP response element-binding protein (CREB) (TORC2) and the expression of the CREB and insulin receptor substrate 2 genes [57] Additionally, by boosting bcl- 2 activity and blocking the proapoptotic Bax, activated CREB also supports beta cell survival [58]
