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Though most of these side effects do reduce once you have been taking the medication for a while, some side effects may persist or be intolerable
Side effects during the first week at 1 mg can be challenging for some people
The dose titration starts at 0.25mg and increases every four weeks through 0.5mg, 1mg, 1.7mg, and 2.4mg, then continues up to 3.6mg and the maintenance dose of 7.2mg at around week 32
Per kg dosage in mice does not scale to humans
The body has learned to adapt
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