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Why is Dihexa classified as a peptidomimetic rather than a peptide
Studies utilizing radioactive proline incorporation assays have confirmed that GHK-Cu increases both collagen synthesis rates and the proportion of newly synthesized collagen that successfully incorporates into extracellular matrix structures
Its principal molecular activity is G-actin sequestration via the conserved 'LKKTET' actin-binding motif in the N-terminal region
The palmitoyl group of Pal-GHK enhances its ability to penetrate the skin, enabling it to pass into deeper layers of the skin when compared to GHK or GHK-Cu [22]
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