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Candidates typically include adults with a Body Mass Index (BMI) of 30 or higher, classified as obese, or those with a BMI of 27 or higher who also face weight-related health challenges such as hypertension, type 2 diabetes, or dyslipidemia
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However, better delineation of the therapeutic and prophylactic roles of L-carnitine in these conditions will require further investigations in controlled, randomized and probably multicentre trials to evaluate the clinical value and the appropriate dosage of L-carnitine in each of these conditions
Nature 446 , 557561 (2007)