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Even in aggressive scenarios for reduced consumption related to GLP-1 use, modest gains to life expectancy can more than offset the impact over time. Indeed, because obesity-related diseases cut years off average lifespans, treatment with GLP-1 drugs can add years (up to 14 years) to the lives of those who take them

Also, because GLP-1 drugs engage the brain's reward circuitry the same system that governs not just craving but everyday motivation prolonged use could, in theory, dampen motivational drive in some people

One caveat was that participants in the mB12/LDFA and BH4 studies had significantly worse markers of glutathione metabolism and chronic oxidative stress at baseline, respectively

Former LA-based celebrity facialist Ingrid Seaburn said she had warned curious clients of her Bondi-based skin health studio about the risks of melanotan, pointing out the only safe tan was a fake tan

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