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If you experience sharp abdominal pain, vomiting, inability to keep food down for more than a few hours, or heartburn that doesn't improve after 23 weeks despite dietary changes, your clinician may recommend dose adjustments, medication changes, or an evaluation for underlying conditions
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No: they do not directly activate the GLP-1 receptor in the same way as semaglutide or liraglutide, and do not have the same clinical evidence
Although the hormones GLP-1 and GIP, as well as their receptors, are closely related, GIP receptor (GIPR) activation seems to be devoid of these actions