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According to NICE guidance (NG28), these medications have demonstrated significant benefits in glycaemic control, with some specific agents (semaglutide, liraglutide, dulaglutide) also showing cardiovascular risk reduction in clinical trials

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411,412 Patient-derived tumor organoids (PDOs) are three-dimensional (3D) microtissue models developed in vitro from normal or malignant tissues

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doi: 10.1016/j.atherosclerosis.2022.03.032