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One well-documented interaction is with certain anti-epileptic drugs: high-dose pyridoxine may reduce the plasma levels of phenytoin and phenobarbital by enhancing their hepatic metabolism, potentially diminishing their anticonvulsant efficacy
It is a synthetic form of B12 with cyanide attached to the cobalamin (the B12)
Vitamins C, E and A, beta-carotene (carotenoids), and polyphenols are among the antioxidants many dermatologists recommend including in your diet to help prevent skin-related issues
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Scientific References Hydroxocobalamin: a medicine to treat vitamin B12 deficiency
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