If you don't treat it, it can cause serious complications that are often life-threatening
This means its absorbed faster
Anders Schultz, MD, FRCPC Edmonton, AB, Canada Send page to friend via: Share via: You may also be interested in
Cagrilintide, the second generation (2020s) Novo Nordisk took the Pramlintide concept and applied the same half-life extension strategy that they used with Semaglutide: Kept the proline substitutions (anti-amyloid) Added a C20 fatty diacid via a -Glu linker to a lysine residue, albumin binding Additionally stabilized the N- and C-terminal positions Result: Cagrilintide with a half-life of 6.6 days (vs 50 minutes for Pramlintide)
Haasch D, Berg C, Clampit JE, Pederson T, Frost L, Kroeger P, et al