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Jin J, Byun JK, Choi YK, Park KG
However, looking at the aspect ratio (defined as the ratio of the major to minor axes lengths), we observed an elongation of the mitochondria (Fig
Age-related cognitive decline Normal aging is associated with mild cognitive impairments that are caused by various neuroanatomical changes, including alterations in brain receptors, myelin dystrophy, loss of dendritic spines, and changes in nerve transmission (146)
In rat models of PD, IN DFO has been reported to protect dopaminergic neurons in the substantia nigra and ameliorate motor deficits, suggesting IN DFO reaches the midbrain regions at pharmacologically active concentrations (Hanson et al., 2009)
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