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Others develop a tolerance to the drugs, and over time, they may stop working as well
The challenge lies in ensuring training provides adequate stimulus for muscle growth while managing potential energy fluctuations during the adaptation period
When it comes to weight management, certain peptides, particularly GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptor agonists, play critical roles
Current Pharmaceutical Design, 2014, 20(7):1121-1125 2.Sikiric P, Seiwerth S, Brcic L, Sever M, Klicek R, Radic B, Drmic D, Ilic S, Kolenc D
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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