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Despite significant progress observed in clinical trial development, there remains a scarcity of published clinical data, particularly regarding long-term safety, efficacy across diverse populations, and real-world effectiveness

In the phase 2 trial, the 8mg group achieved approximately 17.3% weight reduction at 24 weeks, a rate of loss that would not be possible without profound appetite suppression driving significant caloric deficit

That doesn't seem like a lot, amounting to an estimated 854,000 Americans without diabetes using GLP-1 drugs to lose weight in 2022, but the drugs are costly, and can run close to $1,000 or more a month, researchers found

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She immediately noticed fewer cravings for foods that had previously been difficult to eat in moderation