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Dawes, Glutathione synthetase is dispensable for growth under both normal and oxidative stress conditions in the yeast Saccharomyces cerevisiae due to an accumulation of the dipeptide gamma-glutamylcysteine

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This "whole-body" approach is central to how we think about supplementation

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Int J Obes (Lond) (2007) 31(9):14208

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10.1016/S0304-3835(97)00261-9 30

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Packer M, Butler J, Zannad F, et al

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