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The combination approach appears most promising for long-term sustainability

Researchers say they dont even have genetic proof that humans naturally produce it, and we dont even know which specific receptors it might bind

Versus biomimetic cosmetic peptides (matrixyl, argireline, acetyl hexapeptide): these peptides are protein fragments with targeted activity (calcium neurotransmission modulation for argireline, matrix stimulation for matrixyl)

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10.1038/s41386-019-0411-y 28 RourkeE.LawF