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[3] When used alone at recommended doses, phentermine has not been associated with such valvular or pulmonary complications, since it lacks direct agonism at the 5-HTB receptors implicated in fenfluramines toxicity
Research indicates that intravenous, liposomal and sublingual (applied under the tongue) methods of supplementation may be better choices over oral supplementation because they are not broken down during digestion which can prevent adequate absorption
doi: 10.1016/j.phymed.2025.157164 227 YuanSWangYLiZChenXSongPChenAet al
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