According to current statistics, cases of unwanted side effects are very rare
Cold potato salad, for instance, typically produces a lower glucose spike than freshly cooked hot chips
They require a specialized, active transport mechanism, scientifically referred to as the "carnitine shuttle," to gain entry into the mitochondrial matrix where they can be burned for fuel
This efficacy limitation, rather than safety concerns, halted further development
As Kannt & Pfenninger highlight in Frontiers in Physiology , maintaining NAD levels is a cornerstone of metabolic health, supporting mitochondrial function and improving resistance to metabolic stress (Kannt & Pfenninger, Frontiers in Physiology )