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It does not appear to have toxic effects on the major organs, and it does not affect the endocrine (hormonal) system significantly
In addition, this effect may be enhanced in older adults, as they have a stronger and more diffuse oxygen consumption during cognitive effort (Rodrguez-Nieto et al., 2024)
These findings suggest that while FOXO4 is involved in the senescence pathway, it also plays a role in maintaining the viability of senescent Leydig cells by suppressing their apoptotic response, which could contribute to the accumulation of senescent cells [1]
10.1016/0360-3016(94)90017-5 Int
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