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Description

A key feature of obesity is an excessive accumulation of body fatalso known as adipose tissuethat is metabolically active, releasing hormones and inflammatory markers that contribute to several conditions, including insulin resistance, inflammation, and cardiovascular damage.[8] Obese individuals therefore have an increased risk of developing numerous chronic conditions, including type 2 diabetes, cardiovascular disease, hypertension, and certain cancers.[9] Obesity rates have surged, nearly doubling since the early 2000s

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Nat Rev Mol Cell Biol 21(8):439458

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For people using the medication as part of a weight management plan, reduced potency can lead to slower progress or stalled weight loss

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