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This third mechanism adds a layer of GI disruption on top of the GLP-1-mediated delayed gastric emptying that both drugs share
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it reveals predispositions in peptide and metabolic genetic pathways
Doses above ~500 mcg/day are not generally linked to added benefit in the reference literature, and none of this reflects proven human efficacy
Abdominal fat provides convenient systemic administration when local injection proves difficult or for diffuse ankle issues
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