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Garg R, Kumbkarni Y, Aljada A, Mohanty P, Ghanim H, Hamouda W et al
In the United States, FDA guidelines indicate these medications for: Adults with a BMI of 30 or higher (obesity) Adults with a BMI of 27 or higher who also have at least one weight-related health condition, such as type 2 diabetes, high blood pressure, high cholesterol, or obstructive sleep apnea You should discuss GLP-1 medications with a physician if you have any of the following, as they may affect which medication is appropriate or require additional monitoring: Personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN2) a contraindication for all GLP-1 drugs History of pancreatitis Kidney disease or a history of gallstones Pregnancy or plans to become pregnant History of eating disorders The Critical Factor Most People Overlook: Muscle Loss Here is something that rarely appears in GLP-1 marketing: these medications can cause significant muscle loss alongside fat loss, particularly at the aggressive weight loss rates they enable
It slows down the emptying of the stomach and it leads to decreased appetite. Its original purpose was for people with type 2 diabetes, but its success in decreasing appetite and hunger levels has also made it a desirable option for people desperate to lose weight
& Ramachandran, A
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