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They included patients with a recent history of obesity, and excluded those with diabetes or who had been prescribed another antidiabetic drug
doi: 10.1016/j.clim.2020.108544 29 JainS
For half-life and dosing rhythm: Sermorelin's very short half-life means its effect is brief and tightly tied to the timing of administration
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Phentermine is the opposite on this point: it reaches its peak concentration within a few hours and clears quickly, which fits its role as a short-term push
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