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A phase I trial (NCT02415621) evaluating adaptive dosing of abiraterone in metastatic castration-resistant prostate cancer demonstrated that intermittent androgen pathway suppression based on PSA dynamics could delay resistance and reduce cumulative toxicity
What Studies Show: Explored for anti-aging, body composition improvement, and even cognitive support
Given variability in response, genotype-guided selection may identify subgroups most likely to benefit
Vitamin D is critical for musculoskeletal health, with deficiency leading to osteomalacia in adults and rickets in children due to impaired bone mineralisation [72]
All in all, the lack of GPX1 aggravates the damage caused by oxidative stress to tissues and organs
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