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doi:10.1002/jcph.2373 195

Under normal conditions, the liver neutralizes NAPQI using glutathione, a natural antioxidant

By identifying biological mechanisms rather than isolated genes, the analysis helps explain why some patients experience strong, durable benefit while others do not, supports quantitative prediction of response magnitude and tolerability, and provides a mechanistic foundation for more precise prescribing and drug-specific stratification as the GLP-1 class continues to expand

10.2337/dc17-1902 10

Nondrug therapies that may help include: gentle stretching and toning exercises gentle massage heat therapy water therapy Anxiety and depression Anxiety and depression are common among people with ME/CFS