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This side effect is usually mild to moderate and tends to improve after the first few weeks of treatment

To counteract the detrimental impact of ROS, superoxide dismutase (SOD) facilitates the dismutation process, transforming superoxide radicals (O 2 - ) into oxygen molecules (O 2 ) and hydrogen peroxide (H 2 O 2 ), whereas glutathione peroxidase (GPx) converts H 2 O 2 to H 2 O

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This study suggests that copper-coordination and ROS production might be more prevalent in intrinsically disordered proteins than realized