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Michael Blaha, MD (Johns Hopkins Medicine, Baltimore, MD), who wasnt involved in the study, told TCTMD the study findings and subsequent approval could have profound implications for primary and secondary prevention
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When prescribing an extended-release formulation of tramadol, clinicians must inform the patient to swallow the tablet whole and not chew, crush, dissolve, or split it into smaller pieces (61)
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Gallbladder or bile duct problems Blockages in the bile system can also increase bilirubin, leading to dark urine
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