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Both compounds cause gastrointestinal side effects like nausea and diarrhea, but mazdutide side effects are generally milder and more manageable
Retatrutide's triple receptor activity produces larger total weight reduction in clinical trials (~24-29% vs ~20-22% for tirzepatide), but the side effect profile is more demanding during titration
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Exaggerated claims should trigger skepticism
Aim for at least two strength sessions per week to support muscle growth, says Dr
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