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Many patients prefer evening dosing because any initial nausea or digestive discomfort occurs while they are winding down or sleeping, rather than during work or social obligations
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The overproduction of 5-oxoproline exceeds the capacity of 5-oxoprolinase, and 5-oxoproline therefore accumulates in body fluids and is excreted in the urine
Do not use examples above 3 mL when the vial cannot safely hold more than 3 mL
So I dont think its necessarily related to the GLP-1s per se
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