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However, there were no statistical differences in PKA ( P = 0.3573), p-PKA ( P = 0.2439), CREB ( P = 0.7447) or p-CREB ( P = 0.3302) expression levels between the OA and OA + saline groups

Any concerns about digestive symptoms, nutritional adequacy, or the appropriateness of fibre supplementation should be discussed during these appointments or sooner if symptoms are troublesome