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However, in diseases such as T1DM, psoriasis, autoimmune hepatitis, and vasculitis, studies have also suggested that amino acid metabolic reprogramming may participate in the regulation of macrophage function and may exhibit directional effects and context-dependent differences that vary with tissue niche, stimulus spectrum, and disease stage (59, 8082)
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Free Radic Res 31:525534 Upadhyaya CP, Venkatesh J, Gururani MA, Asnin L, Sharma K, Ajappala H, Park SW (2011) Transgenic potato overproducing L-ascorbic acid resisted an increase in methylglyoxal under salinity stress via maintaining higher reduced glutathione level and glyoxalase enzyme activity
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