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These new dynamic steady states are achieved after about 150 hours

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[2] Based on breast milk concentrations from 3 women taking 150 to 200 mg topiramate daily, it was estimated that a breastfed infant (assuming a milk intake of 150 mL/kg/day) would receive approximately 0.1 to 0.7 mg/kg/day or 3% to 23% of the maternal weight-adjusted dose

Metabolomics not only identifies differential metabolites but also links them to transcriptomic changes and cellular outcomes, offering a systems-level view of microbial synergy and host response (Sulaiman et al., 2024