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Phase 3 REDEFINE 1 and 2 trials have confirmed clinically significant weight-reducing effects in adults with obesity, both with and without T2D [58,59]

Patients were invited to participate in the study on an entirely voluntary basis and were at liberty to stop taking the weight-loss medication or withdraw from the study at any time

They use 5mg vials during the titration phase when doses are low and switch to 10mg vials once they reach their maintenance dose

In this review, the relations based on the currently available literature were explored

The clinical impact of GLP-1 receptor agonists in type 2 diabetes: focus on the Long-Acting analogs