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reported valvular abnormalities in 24% and recommended to perform an echocardiogram at first presentation

Some preclinical work explores FOXO4-p53-targeting peptides against senescent cancer cells, and the developer has discussed cancer as a research interest, but there is no human evidence that FOXO4-DRI treats cancer

However, despite these complications, several patients are older than the mean expected life expectancy for patients with vEDS 25 and 11 patients have not had any GI or vascular complications, although 4 of these 11 are pediatric patients

As this is a medical procedure, make sure you are well hydrated and have consumed a full meal before starting treatment