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Ryan, MD, professor emerita at Pennington Biomedical Research Center, discussed some of the advantages orforglipron has over other incretin-based drugs

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The therapy also improved cardiovascular risk factors despite a 20.8% discontinuation rate due to gastrointestinal side effects

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For perspective on scale: the two ED trials together enrolled 20 subjects

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Generally, many patients may notice improvements in their blood sugar levels within a few weeks of beginning GLP-1 therapy

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