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CJC-1295 is a tetrasubstituted version of the peptide that is also modified by adding a drug affinity complex (DAC) component called N-epsilon-3-maleimidopropionamide, which appears to bind to plasma proteins and may improve CJC-1295 pharmacokinetics
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In addition to neuroimaging, peripheral blood testing including vascular endothelial growth factor, fibroblast growth factor, and -amyloid peptide 40 was performed, and advanced polychromatic flow cytometry was used to phenotype circulating mononuclear cells to assess angiogenic activity (Callahan et al
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