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Your baseline metabolic rate, insulin resistance severity, genetic factors, and hormonal profile all affect treatment response

Quick answer: Skip L-carnitine if you expect it to replace a calorie deficit, if you are pregnant or breastfeeding without medical guidance, if you have seizure history, kidney disease, cardiovascular risk concerns, hypothyroidism concerns, or if you are on medications that make supplement use a clinician-level decision

Not all patients respond to GLP-1 therapy in the same way

Additionally, better blood sugar control reduces the risk of heart attack, stroke, and other heart-related conditions

Diabetologia 65 , 19811993 (2022)