The human evidence is limited, but the mechanistic rationale is enough that this remains an active research area
Rebouche, C.J., Mack, D.L
Excretion Pathways Limited data on combined excretion indicates[21]: Primarily renal elimination of peptide fragments from all components Hepatic metabolism contributes to overall clearance Copper recycling through normal physiological pathways (GHK-Cu component) No evidence of accumulation in chronic dosing studies of individual components BPC-157 detectable in urine for up to 4 days
Cell Journal (Yakhteh) 22(Suppl 1):29 Ruppert KA, Nguyen TT, Prabhakara KS, Toledano Furman NE, Srivastava AK, Harting MT et al (2018) Human mesenchymal stromal cell-derived extracellular vesicles modify microglial response and improve clinical outcomes in experimental spinal cord injury
Embracing a regimen that combines a nutritious diet with skin-focused products can be key to achieving and maintaining clear skin