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Cytoscape software (version 3.9.1) was used for visualization and analysis of the PPI network
Multi-Functional Regenerative Peptide Stem Cell Mobilisation & Scar Reduction (PubMed, 2012) A comprehensive review of TB4s biological properties published in Expert Opinion on Biological Therapy confirmed that TB4 is released by platelets, macrophages, and multiple cell types following injury, where it protects cells and tissues from further damage while reducing apoptosis, inflammation, and microbial growth
It protects cells from apoptosis and may be useful in staving off heart, eye, brain, and muscle diseases
In these cells, the transcription factor FOXO4 is highly upregulated and physically sequesters the tumor suppressor p53 in nuclear foci, preventing p53 from triggering apoptosis
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