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How much lowering of blood pressure is required to prevent cardiovascular disease in patients with and without previous cardiovascular disease

Lilly has also taken a vocal stance against the use of obesity medicine for cosmetic weight loss

The FDA added it to injectable semaglutide in January 2025, and it climbs the dose axis like everything else. Burning or tingling skin tracks the dose, not the weight lost, and an active-comparator study put the risk about twice that of another weight-loss drug. The mechanism remains unsettled

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That difference is not considered clinically significant for most patients