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Meanwhile, 5-Amino-1MQ helps inhibit an enzyme called NNMT, which normally diverts NAD+ precursors away from energy production pathways
To enhance ferroptosis-based cancer therapy via glucose metabolism modulation, dopamine (DA) and Fe ions were co-coordinated to encapsulate bacterial outer membrane vesicles (OMVs), followed by in situ growth of ultrasmall gold nanoparticles (Au NPs) on the surface to construct a multifunctional nanoplatform (OMV-DFA) [145]
In both processes, glutathione also plays a central role due to its particularly favourable redox capacity and its effects which cannot be replaced by other substances
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doi: 10.3892/ol.2017.6638
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