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It is a transcription factor that translocates into the nucleus and binds in the promoter regions of detoxifying and antioxidants genes [27]
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Protective Role of Interleukin-10 in Atherosclerosis
IGFBPs can also act to guide IGF-1 to specific tissues, or even to inhibit or potentiate IGF-1 actions by acting as an independent substrate for the IGF-1R and/or other specific membrane, intracellular or nuclear receptors [7]
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