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Because of these differences, a recent article published in the European Journal of Clinical Nutrition stated, Thus, it is prudent to use cyanocobalamin wherever required instead of methylcobalamin alone in order to address both the neurological and haematopoietic pathways. 3 The fact is cyanocobalamin can be converted into both methylcobalamin and adenosylcobalamin in the body

Therefore, it is of critical importance that the extracellular glutamate concentration must be kept enough low due to the toxicity of glutamate in high concentrations

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120 LiuY.JiJ.ZhangW.SuoY.ZhaoJ.LinX.et al (2019)

Pharmaceutical inhibitors like finasteride block both types systemically, which explains their effectiveness but also their side effect profile